Interoception: Spinal sensory neurons that innervate the intestines
Author: Truong Ly1, Zachary A Knight2
Affiliation:
1 Department of Physiology, Kavli Institute for Fundamental Neuroscience, Neuroscience Graduate Program, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.
2 Department of Physiology, Kavli Institute for Fundamental Neuroscience, Neuroscience Graduate Program, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA. Electronic address: zachary.knight@ucsf.edu.
Conference/Journal: Curr Biol
Date published: 2023 Sep 25
Other:
Volume ID: 33 , Issue ID: 18 , Pages: R945-R947 , Special Notes: doi: 10.1016/j.cub.2023.07.066. , Word Count: 49
The gut is innervated by sensory neurons that relay mechanical and chemical signals to the brain. Two new studies characterize the spinal sensory neurons that innervate the intestines and reveal a role for Piezo2 in these cells in sensing colonic distension and regulating gastrointestinal motility.
PMID: 37751704 DOI: 10.1016/j.cub.2023.07.066
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