Interoception: Spinal sensory neurons that innervate the intestines


Author: Truong Ly1, Zachary A Knight2

Affiliation: <sup>1</sup> Department of Physiology, Kavli Institute for Fundamental Neuroscience, Neuroscience Graduate Program, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

<sup>2</sup> Department of Physiology, Kavli Institute for Fundamental Neuroscience, Neuroscience Graduate Program, Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA. Electronic address: zachary.knight@ucsf.edu.
Conference/Journal: Curr Biol
Date published: 2023 Sep 25
Other:
 Volume ID: 33   ,  Issue ID: 18   ,  Pages: R945-R947   ,  Special Notes: doi: 10.1016/j.cub.2023.07.066.   ,  Word Count: 49  
    The gut is innervated by sensory neurons that relay mechanical and chemical signals to the brain. Two new studies characterize the spinal sensory neurons that innervate the intestines and reveal a role for Piezo2 in these cells in sensing colonic distension and regulating gastrointestinal motility.





PMID: 37751704 DOI: 10.1016/j.cub.2023.07.066