The Bioelectric Circuitry of the Cell.
Author: Tuszynski JA4,5,6 in Makarov S1, Horner M2, Noetscher G3
Affiliation:
1Massachusetts General Hospital, Boston, MA, USA
2ANSYS, Inc., Evanston, IL, USA
3Worcester Polytechnic Institute, Worcester, MA, USA
4Department of Oncology, University of Alberta, Edmonton, AB, Canada
5Department of Physics, University of Alberta, Edmonton, AB, Canada
6DIMEAS, Politecnico di Torino, Turin, Italy
Conference/Journal: SourceBrain and Human Body Modeling: Computational Human Modeling at EMBC 2018 [Internet]. Cham (CH): Springer;
Date published: 2019 Aug 28
Other:
Word Count: 122
Excerpt
This chapter presents an overview of electric conduction in living cells when viewed as a composition of bioelectric circuits. We review the cell’s components that are known to exhibit electric conduction properties and represent them as parts of a complex circuitry. In particular, we discuss conductivity of the membrane, ion channels, actin filaments, DNA, and microtubules, each of which play important roles in the biological functioning of the cell. A new picture emerges where electrical conduction within the cell is taking place in an integrated fashion and may explain synchronization and orchestration of the cell dynamics.
Copyright 2019, The Author(s).
Sections
11.1. Introduction
11.2. Ion Channel Conduction Effects
11.3. Actin Filament Conductivity
11.4. Microtubule Conductivity
11.5. Conclusions
Acknowledgments
References
PMID: 31725231
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