Author: Yu Y1,2, Gao Q1,2, Xia W3, Zhang L4, Hu Z2, Wu X3, Jia X3
1Department of Physiology, Bengbu Medical College, 2600 Dong Hai Avenue, Bengbu 233030, China.
2Science Research Center, Bengbu Medical College, 2600 Dong Hai Avenue, Bengbu 233030, China.
3Department of Epidemiology and Statistics, Bengbu Medical College, 2600 Dong Hai Avenue, Bengbu 233030, China.
4Department of Neurology, First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China.
Conference/Journal: Biomed Res Int.
Date published: 2018 Jul 3
Other: Volume ID: 2018 , Pages: 4135104 , Special Notes: doi: 10.1155/2018/4135104. eCollection 2018. , Word Count: 237
This study aimed to investigate the role of different types and frequencies of physical exercise in biomarkers of oxidative stress among middle-aged and elderly community residents with essential hypertension in China. A community-based cross-sectional survey was undertaken in 7 subdistricts. Individuals, 45-79 years old, with essential hypertension (n = 402) and without cardiovascular disease (n = 1047) were included. Superoxide dismutase (SOD) activities and plasma levels of malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) were determined. Multilevel linear regression was used to estimate the associations between various types of physical exercise and oxidative stress biomarker levels. Participants engaged in high frequency walking/square dancing or taiji/yoga demonstrated decreased systolic blood pressure in both groups; however, diastolic blood pressure decreased only among individuals with hypertension participating in walking/square dancing. In individuals with hypertension, MDA levels decreased in those participating in walking/square dancing, SOD activity increased in those participating in walking/square dancing, and 4-HNE levels decreased in those involved in taiji/yoga. In individuals without cardiovascular disease, MDA levels decreased in those involved in walking/square dancing or taiji/yoga, SOD activity increased in those performing walking/square dancing, and 4-HNE levels decreased in those involved in taiji/yoga. Oxidative stress marker levels also improved in those involved in walking/square dancing or taiji/yoga groups as the exercise frequency increased. Thus, frequent participation in walking/square dancing or taiji/yoga effectively decreases hypertension-related oxidative stress biomarker levels.
PMID: 30065938 PMCID: PMC6051290 DOI: 10.1155/2018/4135104