[Histomorphological analyse of accelerating the fibrocartilage layer repair of patella-patellar tendon junction in rabbits by low intensity pulsed ultrasound stimulation].
Author: Zhang B, Lü H, Hu J, Xu D, Zhou J, Wang Y.
Affiliation:
Department of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008; Department of Spinal Surgery, Central Hospital of Yongzhou, Yongzhou Hunan 425000,China.
Conference/Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban.
Date published: 2013 Aug
Other:
Volume ID: 38 , Issue ID: 8 , Pages: 838-42 , Special Notes: [Article in Chinese] , Word Count: 179
Objective: To analyse the effect of low intensity pulsed ultrasound stimulation (LIPUS) on accelerating the fibrocartilage layer repair of patella-patellar tendon junction. Methods: A total of 60 mature female New Zealand white rabbits undergoing standard partial patellectomy were divided into 2 groups randomly. The control group was given comfort threatment and the treatment group was given LIPUS treatment starting from day 3 to the end of week 6 postoperatively. The scheduled time points of animal euthanization would be at week 6, week 12 and week 18 postoperatively. The patella-patellar tendon (PPT) complex would be harvested and cut into sections after decalcification for H&E staining, Safranine o/fast green staining. The thickness and gray value of fibrocartilage layer were analyzed by SANO Microscope Partner image analyzer. Results: At week 6, week 12 and week 18 postoperatively, the fibrocartilage layer in the treatment group was significantly thicker than that in the control group (P<0.01), and the gray value of fibrocartilage layer was significantly smaller than that in the control group (P<0.01). Conclusion: LIPUS helps to accelerate the fibrocartilage layer repair of patella-patellar tendon junction in rabbit models.
PMID: 23981992
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