A novel acetylcholine bioensor and its electrochemical behavior.
Author: Wang W, Deng Y, Li S, Liu H, Lu Z, Zhang L, Lin L, Xu L.
Affiliation:
Key Laboratory of Green Packaging and Application of Biological Nanotechnology, Hunan University of Technology, Zhuzhou 412007, China.
Conference/Journal: J Biomed Nanotechnol.
Date published: 2013 Apr
Other:
Volume ID: 9 , Issue ID: 4 , Pages: 736-40 , Word Count: 84
A novel type of acetylcholine electrochemical biosensor was successfully fabricated by dropping beta-cyclodextrin solution, acetylcholinesterase solution and Nafion-methanol solution to the homemade nano-porous pseudo carbon paste electrode (nano-PPCPE) as working electrode, and then the electrochemical behavior of the as-prepared biosensor was studied through the acetylthiocholine iodide (ATChI). It was shown that the modified nano-PPCPE displays a high selectivity and sensitivity. The acetylcholine biosensor showed the linear range from 5 x 10(-6) M to 2 x 10(-4) M with the detection limit of 1.5 x 10(-7) M.
PMID: 23621036
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