Effect of Radio Frequency Waves of Electromagnetic Field on the Tubulin.

Microtubules (MTs) are macromolecular structures consisting of tubulin heterodimers and present in almost every eukaryotic cell. MTs fulfill all conditions for generation of electromagnetic field. Microtubules are electrically polar due to the electrical polarity of a tubulin heterodimer which has calculated static electric dipole moment of about 1000 Debye, which makes them capable of being aligned parallel to the applied electromagnetic field direction. Tubulin heterodimers were purified from rat brains. MTs were obtained by polymerization in vitro. Samples of microtubules adsorbed under and without electromagnetic fields with radio frequency 900 Hz. Our results demonstrate the effect of electromagnetic field with 900 Hz frequency to change the structure of MTs. In this paper, a related patent used that will help to better understand the studied subject.
PMID: 23470160