Sustained effects of a mindfulness-based stress-reduction intervention in type 2 diabetic patients: design and first results of a randomized controlled trial (the Heidelberger Diabetes and Stress-study).

Author: Hartmann M, Kopf S, Kircher C, Faude-Lang V, Djuric Z, Augstein F, Friederich HC, Kieser M, Bierhaus A, Humpert PM, Herzog W, Nawroth PP.
Affiliation:
Department of Medicine II and Psychosomatics, University of Heidelberg, Heidelberg, Germany. mechthild.hartmann@med.uni-heidelberg.de
Conference/Journal: Diabetes Care.
Date published: 2012 May
Other: Volume ID: 35 , Issue ID: 5 , Pages: 945-7 , Word Count: 149


OBJECTIVE:
To determine whether a mindfulness-based stress reduction (MBSR) intervention is effective for reducing psychosocial distress (i.e., depression, psychosocial stress) and the progression of nephropathy (i.e., albuminuria) and for improving the subjective health status of patients with type 2 diabetes.
RESEARCH DESIGN AND METHODS:
Patients with type 2 diabetes and microalbuminuria were randomized to a mindfulness-based intervention (n = 53) or a treatment-as-usual control (n = 57) group. The study is designed to investigate long-term outcomes over a period of 5 years. We present data up to the first year of follow-up (FU).
RESULTS:
At FU, the MBSR group showed lower levels of depression (d = 0.71) and improved health status (d = 0.54) compared with the control group. No significant differences in albuminuria were found. Per-protocol analysis also showed higher stress reduction in the intervention group (d = 0.64).
CONCLUSIONS:
MBSR intervention achieved a prolonged reduction in psychosocial distress. The effects on albuminuria will be followed up further.
PMID: 22338101

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