Biomagnetic and bioelectric detection of gastric slow wave activity in normal human subjects-a correlation study.
Author: Somarajan S, Muszynski ND, Obioha C, Richards WO, Bradshaw LA.
Affiliation:
Department of Surgery, Vanderbilt University, Nashville, TN, USA. Department of Physics & Astronomy, Vanderbilt University, Nashville, TN, USA.
Conference/Journal: Physiol Meas.
Date published: 2012 Jul
Other:
Volume ID: 33 , Issue ID: 7 , Pages: 1171-9 , Word Count: 124
We measured gastric slow wave activity simultaneously with a Superconducting Quantum Interference Device (SQUID) magnetometer, mucosal electrodes and cutaneous electrodes in 18 normal human subjects (11 women and 7 men). We processed signals with Fourier spectral analysis and SOBI blind-source separation techniques. We observed a high waveform correlation between the mucosal electromyogram (EMG) and multichannel SQUID magnetogastrogram (MGG). There was a lower waveform correlation between the mucosal EMG and cutaneous electrogastrogram (EGG), but the correlation improved with the application of SOBI. There was also a high correlation between the frequency of the electrical activity recorded in the MGG and in mucosal electrodes (r = 0.97). We concluded that SQUID magnetometers noninvasively record gastric slow wave activity that is highly correlated with the activity recorded by invasive mucosal electrodes.
PMID: 22735166
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