Author: Xu WR, Hua BJ, Hou W, Bao YJ.
Affiliation: Beijing University of CM, Beijing 100029, China.
Conference/Journal: Zhongguo Zhen Jiu.
Date published: 2010 Jun
Other: Volume ID: 30 , Issue ID: 6 , Pages: 457-60 , Special Notes: [Article in Chinese] , Word Count: 161
OBJECTIVE: To seek the effective treatment for peripheral neuropathy induced by chemotherapeutic drugs. METHODS: Sixty-four cases of peripheral neuropathy induced by Paclitaxel or Oxaliplatin were randomly divided into an acupuncture group and a medication group, 32 cases in each group. The acupuncture group was treated with therapeutic principle of dredging meridians and collaterals, tonifying qi and eliminating blood stasis, supplementing liver and kidney, nourishing blood and tendon. Hegu (LI 4), Taichong (LR 3), Zusanli (ST 36), Qihai (CV 6) and Quchi (LI 11) etc. were selected. The medication group was treated with intramuscular injection of Cobamamide. The neurotoxicity of two groups was compared with questionnaire of peripheral neuropathy induced by chemotherapeutic drugs before and after treatment. RESULTS : The total effective rate for sensory nerve disorder of acupuncture group was 66.7% (20/30), which was superior to that of 40.0% (12/30) in medication group (P < 0.05). CONCLUSION: Acupuncture is more effective than Cobamamide for treatment of peripheral neuropathy induced by chemotherapeutic drugs, especially for moderate and severe sensory nerve disorder induced by paclitaxel.