[Effect of nitric oxide on noradrenergic function and skin electric resistance of acupoints and meridians]

Author: Liang Y, Ma SX, Chen JX
School of Fundamental Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China
Conference/Journal: Zhen Ci Yan Jiu.
Date published: 2008 Jun
Other: Volume ID: 33 , Issue ID: 3 , Pages: 213-6 , Special Notes: [Article in Chinese] , Word Count: 97

Most acupuncture points correspond to low skin-resistance points (LSRP) on the body surface along the meridians. We did three experiments which conformed that the skin nitric oxide (NO) concentration and expression of neuronal nitric oxide synthesis (nNOS) were higher than those in non-acupoints, and non-meridian control points. Noradrenaline (NE) synthesis/release was modulated by exogenous NO donor and selective inhibitor of nNOS in the skin acupoints/meridians. Skin electrical currents in low skin resistance points were modified by L-arginine-derived NO synthesis and NE. As a conclusion, NO-NE contribute to low resistance characteristics of acupoints and meridians.
PMID: 18807729