Immune regulation effect of emitted qi on immunosuppressed animal model

Author: Zhang Li//Yan Xuanzuo//Wang Shuhua//Tao Jundi//Gu Ligan//Xu Yin//Zhou Young//Liu Dong
Affiliation: Institute of Qigong Science, Beijing College of Traditional Chinese Medicine, Beijing, China [1]
Conference/Journal: 1st World Conf Acad Exch Med Qigong
Date published: 1988
Other: Pages: 27 , Word Count: 468


Recently, there have been many papers about strengthening the immune function of an organism by emitted qi, but few papers deal with the immune regulation effect of the emitted qi on immunosuppressed organisms. The present paper reports the immunosuppressed model of mice induced by cyclophosphamide (CY), which is used to investigate the immune regulation effect of the emitted qi.

In this experiment, NIH mice were divided randomly into three groups (I) CY group: CY 2 mg/(20 mg body weight) were administered ip only on the first day. (2) CY+emitted qi group: besides CY, mouse received the emitted qi 10-15 min/day for 7 days. (3) Control group: physiological saline 0.Iml/(20mg body weight) was administered ip only on the first day.

Then the thymus index, thymus structure, T cells proliferation and the activity of interleukin-2 (IL-2) were used to investigate the immune regulating effect of the emitted qi on the immunosuppressed model of mouse.

The results are as follows:
Firstly, we found the effect of the emitted qi on mouse thymus A decline of thymus index was seen after CY was given. The index was obviously lower than that of the control group (P<O.OOI). It indicated that proper dosage of CY could injure thymus. But the thymus index in CY+emitted qi group was obviously higher than the CY group (P<O.005). The result showed that the emitted qi could relieve the thymus injury of the mouse induced by CY. Simultaneously, we found that the emitted qi also alleviated injury of the thymus structure of the mouse induced by CY. In comparison with the CY group, the group of CY+ emitted qi showed the following variations. The cortex of thymus was thickened (P<0.001), medulla was thinned (P<O.05) . The number of pyknotic thymocytes obviously decreased, the degenerate or necrotic epithelia-reticular cells and medullary Hassall's corpuscles obviously decreased too (P<O.001).

Secondly, we found the effect of the emitted qi on the mouse spleen T Iymphocyte. It was seen that T cell proliferation rate of Group II was lower than that of the control group (P<0.01) . However, the T cell proliferation rate of Group II was obviously higher than Group I. It indicated that CY could suppress the T cell proliferation of the mouse spleen. But the emitted qi could relieve the suppression induced by CY. We also found CY could suppress the IL-2 activity of the T cells of the mouse spleen, as compared with the control group (P<0.01). The emitted qi could also relieve the suppression induced by CY (P<O.01).

At present, it is generally accepted that qigong could improve immune function, our experimental results also proved that the emitted qi can induce the biological effect to enhance the cell-mediated immune response of the immunosuppressed model of the mouse.

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