Author: Khondkar S 1//Fujimoto T 2//Yamaguchi K 1//Masud M 1////
Affiliation:
Division of Nuclear Medicine, Cyclotron Radioisotope Center [1]//Department of Medicine and Science in Sports and Exercise, Postgraduate School of Medicine, Tohoku University (Sendai, Japan) [2]
Conference/Journal: J Intl Soc Life Info Science
Date published: 2003
Other:
Volume ID: 21 , Issue ID: 1 , Pages: 263-267 , Word Count: 127
The target of this study was to clarify the role of regional brain function by applying different exercise loads. This study was composed of two parts (quantitative and semi-quantitative) carried out discretely. Two kinds of exercise tasks (14 and 26 participated) were loaded for 35 minutes followed by FDG injection. 3D brain scans and arterialized venous blood samples were collected during exercise for the quantitative approach. Brain areas activated or deactivated were searched with SPM 99 software. Quantitative analysis showed no activated region when the global value was not corrected at p<0.001 but absolute rate decreased with increase of task load. For image analysis, a linear increase in activity was found with exercise load in motor and pre-motor cortex and deactivation was found mostly in the base of the brain