Niwa Treatment for 20 Years: (1) Secret key to develop biological medicines with effectiveness from natural plants and seeds (2) Introduction of several biological medicines with clinical effectiveness, (3) Topical immunosuppressive agent (“T” ointment) used for the treatment of atopic dermatitis under the rubric of “steroid

Twenty years ago, my son of seven years old suffered from acute myelotic leukemia (AML), and treated with chemotherapy for one year and three months. He died with the greatest pain due to cytotoxic chemotherapy, but not due to leukemia itself. I had treated more than one hundred of the patients with malignancies administered with chemotherapy and radiation before the onset of AML of my son, and almost all of them were dead not due to malignancy itself but due to side effect of chemotherapy and radiation. However, I had been not much impressed to be surprised to see these facts; they were not my family. Since I experienced the most severely painful and miserable death of my son, I thought that main-stream treatment including these cytotoxic treatments such as chemotherapy and radiation do not save the patients while non main-stream treatment, biological medicine including Chinese herbs and health products do the patients neither. Since then, I have been devoted in developing natural medicinal products with clinical effectiveness to treat the malignant patients without side-effects. From twelve years ago, I have succeeded in producing cancer-cidal agents and antioxidants with effectiveness from natural plants and seeds. Besides, topical immunosuppressive agent (“T” agent) widely used for the treatment of atopic dermatitis (AD) under the rubric of “steroid free treatment” has been found to induce carcinogenesis in the skin of mice in our laboratory. Our experiment regarding this carcinogenetic effect of topical “T” agent is explained in this paper.