Functional Analysis of the Brain at Rest Studied by PET and EEG
Author: Itoh M 1//Miyazaki H 2///Tashiro M 1//Xiang XZ 3////
Affiliation:
Division of Nuclear Medicine [1]//Division of Radiopharmaceutical Chemistry[4]//Cyclotron Radioisotope Center, Tohoku University, (Sendai, Japan)//Laboratory of Neuroinformation Science, Tohoku-Gakuin University (Sendai, Japan) [2]//Department of Medicine and Science in Sports and Exercise, Tohoku Univ. Graduate School of Medicine, (Sendai,Japan) [3]////
Conference/Journal: J Intl Soc Life Info Science
Date published: 1997
Other:
Volume ID: 15 , Issue ID: 2 , Pages: 282-292 , Word Count: 173
A regional correlation between EEG fractions and cerebral blood flow (CBF) was investigated by pixel-based statistical analysis. Eight right-handed normal male volunteers were measured twice at the same mental condition, i.e., at rest with eyes closed in a quiet examination room. Regional CBF(rCBF) was measured by positron emission tomography with using H215O slow-bolus injection. Brain rCBF images were then transformed into a standard brain configuration which is based on a sterotaxic brain. There were marked intersubject variations in EEG fractions with negligible intra-subjects difference. Regional CBF differences were noted as relative reduction of rCBF in the second scan mainly in the right hemisphere. Significant correlations were found between rCBF and certain EEG fractions. In particular, regional asymmetry in rCBF (left>right)was found in the frontal and temporal cortices which correlated with fractions of EEG higher than 8Hz. The occipital brain rCBF correlated positively with theta and negatively with alpha and beta-2. It was concluded that the EEG-PET correlation study may be useful for understanding of the human brain.
BACK
