Vagus nerve stimulation: a physical therapy with promising potential for central nervous system disorders
Author: Chaoran Wang#1,2, Bangqi Wu#1, Ruolan Lin1,2, Yupei Cheng1,2, Jingjie Huang1,2, Yuyan Chen1,2, Jing Bai1,2
Affiliation:
1 First Teaching Hospital of Tianjin University of Traditional Chinese Medicine/National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
2 Postgraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Conference/Journal: Front Neurol
Date published: 2024 Dec 13
Other:
Volume ID: 15 , Pages: 1516242 , Special Notes: doi: 10.3389/fneur.2024.1516242. , Word Count: 180
The diseases of the central nervous system (CNS) often cause irreversible damage to the human body and have a poor prognosis, posing a significant threat to human health. They have brought enormous burdens to society and healthcare systems. However, due to the complexity of their causes and mechanisms, effective treatment methods are still lacking. Vagus nerve stimulation (VNS), as a physical therapy, has been utilized in the treatment of various diseases. VNS has shown promising outcomes in some CNS diseases and has been approved by the Food and Drug Administration (FDA) in the United States for epilepsy and depression. Moreover, it has demonstrated significant potential in the treatment of stroke, consciousness disorders, and Alzheimer's disease. Nevertheless, the exact efficacy of VNS, its beneficiaries, and its mechanisms of action remain unclear. This article discusses the current clinical evidence supporting the efficacy of VNS in CNS diseases, providing updates on the progress, potential, and potential mechanisms of action of VNS in producing effects on CNS diseases.
Keywords: central nervous system; clinical application; mechanisms; neurophysiotherapy; vagus nerve stimulation.
PMID: 39734634 PMCID: PMC11671402 DOI: 10.3389/fneur.2024.1516242
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