Vagus Nerve and Gut-Brain Communication
Author: Yiyang Wang1,2, Chenxi Duan1,2, Xinyi Du3, Ying Zhu1,3, Lihua Wang1,3, Jun Hu3,4, Yanhong Sun3
Affiliation:
1 Division of Physical Biology, CAS Key Laboratory of Interfacial Physics Technology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China.
2 University of Chinese Academy of Sciences, Beijing, China.
3 Institute of Materiobiology, College of Sciences, Shanghai University, Shanghai, China.
4 The Interdisciplinary Research Center, Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China.
Conference/Journal: Neuroscientist
Date published: 2024 Jul 23
Other:
Pages: 10738584241259702 , Special Notes: doi: 10.1177/10738584241259702. , Word Count: 127
The vagus nerve, as an important component of the gut-brain axis, plays a crucial role in the communication between the gut and brain. It influences food intake, fat metabolism, and emotion by regulating the gut-brain axis, which is closely associated with the development of gastrointestinal, psychiatric, and metabolism-related disorders. In recent years, significant progress has been made in understanding the vagus-mediated regulatory pathway, highlighting its profound implications in the development of many diseases. Here, we summarize the latest advancements in vagus-mediated gut-brain pathways and the novel interventions targeting the vagus nerve. This will provide valuable insights for future research on treatment of obesity and gastrointestinal and depressive disorders based on vagus nerve stimulation.
Keywords: emotional regulation; feeding behavior; gut-brain axis; vagus nerve; vagus nerve stimulation.
PMID: 39041416 DOI: 10.1177/10738584241259702
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