Effects of exercise interventions on quality of life in patients with breast cancer: A systematic review and network meta-analysis
Author: Bing Han1, Peizhen Zhang1, Haojie Zhao2, Xiaojie Zhang2, Hongyue Gao3, Jiating Dong4, Liqing Zeng1, Peng Pi1, Jiayi Pei2
Affiliation:
1 School of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, China.
2 School of Physical Education, Shandong University, Jinan, China.
3 School of Chemistry and Chemical Engineering, Shandong University, Jinan, China.
4 School of Translation Studies, Shandong University, Weihai, China.
Conference/Journal: Psychooncology
Date published: 2024 Jul 1
Other:
Volume ID: 33 , Issue ID: 7 , Pages: e6370 , Special Notes: doi: 10.1002/pon.6370. , Word Count: 223
Objective:
To compare and rank the effectiveness of four primary categories of exercise modalities (aerobic, resistance, mind-body, and combined exercise [CE]) in improving the Quality of life (QoL) of women with breast cancer in a network meta-analysis (NMA).
Methods:
Articles published in English and indexed in the PubMed (MEDLINE), EBSCO, Web of Science, SPORTDiscus, The Cochrane Library, Google Scholar, PsycINFO, EMBASE, and CINAHL Plus databases were identified from inception to 12 October 2023. Studies that met the eligibility criteria were assessed for risk of bias. A frequentist NMA was conducted to appraise the efficacy of different exercise types.
Results:
This study included 56 studies with 3904 participants. Aerobic, mind-body, and combined exercises effectively improved QoL compared to controls. The surface under the cumulative ranking curve (SUCRA) indicated that CE best improved patients' QoL (SUCRA = 96.7%). Analysis of the secondary outcomes suggests that exercise reduced patients' depression (standardized mean difference [SMD] = -0.38, 95% confidence interval [CI] = -0.70 to -0.06, p < 0.001; I2 = 79%) and anxiety (SMD = -0.50, 95% CI = -0.69 to -0.31, p < 0.001; I2 = 27.4%) but did not affect self-esteem.
Conclusion:
All exercise types but resistance were effective in improving the QoL of women with breast cancer, CE (the combination of aerobic and resistance exercise) had the highest likelihood of being optimal for improving QoL.
Keywords: breast cancer; exercise; mental health; network meta‐analysis; psycho‐oncology; quality of life.
PMID: 38937093 DOI: 10.1002/pon.6370
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