Effects of Tai-Chi on Quality of Life in People With Neurodegenerative Diseases. A systematic Review of Randomised Clinical Trials

Author: Alba Navas-Otero1, Alicia Pineda-Nogueras2, Araceli Ortiz-Rubio1, Andrés Calvache Mateo1, Irene Torres-Sánchez1, Marie Carmen Valenza1, María Granados-Santiago3
1 Department of Physiotherapy, Faculty of Health Sciences, University of Granada, Granada, Spain.
2 MYOSPORT Clinic Fisioterapia Entrenamiento Nutrición, Granada, Spain.
3 Department of Nursing, Faculty of Health Sciences, University of Granada, Granada, Spain.
Conference/Journal: Am J Health Promot
Date published: 2024 Mar 2
Other: Pages: 8901171241233095 , Special Notes: doi: 10.1177/08901171241233095. , Word Count: 246

This systematic review aimed to evaluate the effects of Tai Chi on the health-related quality of life (HRQoL) of people with neurodegenerative diseases.

Data source:
This review followed the guidelines of the updated PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020. A systematic search in five electronic databases (Medline via PubMed, Web of Science, Scopus, PEDro, and OTseeker) was performed.

Study inclusion and exclusion criteria:
Randomized control trials (RCTs) examining Tai Chi interventions to improve HRQoL in patients with neurodegenerative diseases published through March 2023 were included.

Data extraction:
Data were extracted from each study by two independent researchers into a data extraction form based on the Cochrane recommendations. Methodological quality and risk of bias were assessed.

Data synthesis:
A meta-analysis was performed using Review Manager 5.3 software.

Of the 439 records that were screened, eight RCTs met the eligibility criteria. They assessed cognitive decline (n = 2) or Parkinson's disease (n = 6). RCT comparison groups included active interventions or usual care. The duration of Tai Chi therapy ranged from 8 to 24 weeks. A sensitivity analysis using a fixed effect model indicated that Tai Chi therapy significantly increased HRQoL [P < 001, SMD (95% CI) = .41 [.21, .60], I2 = 4%].

Tai Chi can effectively improve the HRQoL of people with neurodegenerative diseases, but the heterogeneity across intervention was relatively high. Further studies are needed as research into the benefits of Tai Chi in neurodegenerative disease rehabilitation is still limited.

Keywords: Parkinson disease; Tai Chi; health-related quality of life; interventions; neurodegenerative; population health; rehabilitation.

PMID: 38430055 DOI: 10.1177/08901171241233095