Utilizing fNIRS to investigate the impact of Baduanjin training on attentional function in post-stroke cognitive impairment patients: a study protocol for a randomized controlled trial
Author: Xingchen Zhou#1,2, Yiwen Wan#2, Zhengxian Xu1, Cancan Yu1, Ziyi Wu2, Zesen Zhuang2, Rui Xia3, Hongyu Wang4, Shangjie Chen5
Affiliation:
1 Graduate School, Bengbu Medical College, Bengbu, 233000, Anhui, China.
2 Department of Rehabilitation, The People's Hospital of Baoan Shenzhen, Bengbu Medical College, Bengbu, 233000, China.
3 Shunde Women and Children's Hospital of Guangdong Medical University(Maternity &, Child Healthcare Hospital of Shunde Foshan), Foshan, China. xiaruitcm@foxmail.com.
4 Graduate School, Bengbu Medical College, Bengbu, 233000, Anhui, China. wanghongyu81920@163.com.
5 Department of Rehabilitation, The People's Hospital of Baoan Shenzhen, Bengbu Medical College, Bengbu, 233000, China. csjmesz@sina.com.
Conference/Journal: BMC Complement Med Ther
Date published: 2024 Jan 11
Other:
Volume ID: 24 , Issue ID: 1 , Pages: 30 , Special Notes: doi: 10.1186/s12906-023-04284-2. , Word Count: 382
Background:
Post-stroke cognitive impairment (PSCI) is a prevalent complication among stroke survivors. It not only directly impacts patients' cognitive abilities but also hampers their capacity to regain independence in daily activities, consequently diminishing their quality of life. Among the various cognitive deficits following stroke, impaired attention is the most frequently observed, influencing not only daily functioning but also higher cognitive functions like working memory, executive functioning, and language.Emerging evidence indicates that Baduanjin, a traditional Chinese exercise, may have a positive impact on enhancing attention in older adults with mild cognitive impairment and stroke survivors. However, the precise mechanisms behind this effect remain unclear. In this study, we employed Baduanjin training as an intervention to address attention decline in post-stroke cognitive impairment patients and to delve into the potential mechanisms through which Baduanjin training may enhance attention in individuals with PSCI.
Methods:
In this prospective randomized controlled trial, we plan to recruit 72 participants diagnosed with post-stroke cognitive impairment (PSCI). These participants will be randomly assigned in a 1:1:1 ratio to one of three groups: Baduanjin training(left hemisphere stroke and right hemisphere stroke) and conventional treatment.The conventional treatment group will receive standard rehabilitation sessions. In addition to conventional treatment, participants in the octogenarian training groups will undergo octogenarian training sessions lasting 40 min, five times a week, over a total period of 12 weeks.The primary outcome measures will include the Montreal Cognitive Assessment (MoCA) scale and the Attentional Lateralization Index. These assessments will be conducted by a trained evaluator before the start of the intervention and at weeks 6 and 12 after the intervention begins.Secondary outcome measures will be assessed using the baseline Mandarin version of the Oxford Cognitive Screening (OCS-P) scale, the simplified Fugl-Meyer Motor Function Assessment (FMA) scale, the Pittsburgh Rehabilitation Participation (PRPS) scale, and the Activities of Daily Living (ADL) scale before and after the intervention, respectively.
Discussion:
This trial aims to examine the impact of Baduanjin training on attentional lateralization among patients with post-stroke cognitive impairment (PSCI). Functional brain imaging utilizing near-infrared spectroscopy will be employed to investigate how Baduanjin exercise influences the structural and functional connectivity of distinct brain regions or brain networks.
Trial registration:
Chictr.org.cn, ID: ChiCTR2300076533 . Registered on 11 October 2023.
Keywords: Attentional lateralization; Baduanjin; Post-stroke cognitive impairment; Randomized controlled trial.
PMID: 38212808 DOI: 10.1186/s12906-023-04284-2
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