Author: Tomonori Koseki1,2, Tomohiko Muratsubaki3, Hiromichi Tsushima4, Yu Morinaga5, Takako Oohashi5, Masahiro Imafuku6, Yuichi Suzuki5, Motoyori Kanazawa3, Shin Fukudo3
1 Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, 980-8575, Japan. firstname.lastname@example.org.
2 Department of Rehabilitation Science, Division of Physical Therapy, Sendai Seiyo Gakuin College, 4-3-55 Nagamachi Taihakuku, Sendai, 982-0011, Japan. email@example.com.
3 Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, 980-8575, Japan.
4 Molecular and Cellular Aging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-Cho, Itabashi-Ku, Tokyo, 173-0015, Japan.
5 Department of Rehabilitation Science, Division of Physical Therapy, Sendai Seiyo Gakuin College, 4-3-55 Nagamachi Taihakuku, Sendai, 982-0011, Japan.
6 Department of Early Childhood Education and Care, Faculty of Education, Musashino University, 1-1-20 Shinmachi, Nishi-Tokyo, Tokyo, 202-8585, Japan.
Conference/Journal: J Gastroenterol
Date published: 2023 Jan 11
Other: Special Notes: doi: 10.1007/s00535-022-01938-9. , Word Count: 231
Irritable bowel syndrome (IBS) is a disorder of brain-gut interactions characterized by abdominal pain and bowel dysfunction. Exercise and mindfulness have been reported to be effective on IBS, but there has been no study of their interaction. In this study, we hypothesized that exercise and mindfulness interactively affect the severity of IBS symptoms.
Subjects were 703 adolescents with 590 women and 113 men. Their IBS status was evaluated with Rome III Diagnostic Questionnaire and IBS Severity Index (IBS-SI). They also fulfilled past exercise experience, athletic performance and exercise enthusiasm, International Physical Activity Questionnaire (IPAQ), Mindful Attention Awareness Scale (MAAS), Kessler 6 Scale (K6), and Perceived Stress Scale (PSS). Statistical analysis was performed using SPSS v25.
In this population, 184 (158 women and 26 men, 14.1%) subjects had Rome III IBS symptoms. IBS subjects scored significantly less in exercise enthusiasm at high school (p = 0.017) and MAAS (p < 0.001) and significantly more K6 (p < 0.001) and PSS (p < 0.001) than non-IBS. The two-way ANOVA on IBS-SI showed a significant main effect of MAAS (p < 0.001) and interaction between MAAS and IPAQ (p = 0.008).
It is suggested that mindfulness per se decreases IBS severity, but that mindfulness and physical activity interactively affect the severity. Further studies on how to design interventional trials for IBS patients with mindfulness and physical exercise are warranted.
Keywords: Brain-gut interactions; Exercise experience; Irritable bowel syndrome; Mindfulness; Physical activity.
PMID: 36629949 DOI: 10.1007/s00535-022-01938-9