Understanding the Pivotal Role of the Vagus Nerve in Health from Pandemics

Author: Claire-Marie Rangon1, Adam Niezgoda2
1 Child Neurologist and Pain Specialist, INWE'CARE Medical Center, 92210 Saint-Cloud, France.
2 Chair and Department of Neurology, University of Medical Sciences, 60-355 Poznań, Poland.
Conference/Journal: Bioengineering (Basel)
Date published: 2022 Jul 29
Other: Volume ID: 9 , Issue ID: 8 , Pages: 352 , Special Notes: doi: 10.3390/bioengineering9080352. , Word Count: 112

The COVID-19 pandemic seems endless with the regular emergence of new variants. Is the SARS-CoV-2 virus particularly evasive to the immune system, or is it merely disrupting communication between the body and the brain, thus pre-empting homeostasis? Retrospective analysis of the COVID-19 and AIDS pandemics, as well as prion disease, emphasizes the pivotal but little-known role of the 10th cranial nerve in health. Considering neuroimmunometabolism from the point of view of the vagus nerve, non-invasive bioengineering solutions aiming at monitoring and stimulating the vagal tone are subsequently discussed as the next optimal and global preventive treatments, far beyond pandemics.

Keywords: COVID-19; HIV; neuroimmunometabolism; non-invasive vagus nerve stimulation; pandemics; prion.

PMID: 36004877 DOI: 10.3390/bioengineering9080352