Author: Jingwen Liao1,2, Yanyu Chen3, Li Cai4, Kun Wang5, Shenghui Wu6, Lan Wu4, Bixiao Song3, Min Hu1, Xiaohui Hou3,7,8
1 Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion, Guangzhou Sport University, Guangzhou, China.
2 Scientific Research Center, Guangzhou Sport University, Guangzhou, China.
3 Department of Sports and Health, Guangzhou Sport University, Guangzhou, China.
4 Department of Martial Arts, Guangzhou Sport University, Guangzhou, China.
5 Department of Breast Cancer, Cancer Center, Guangdong Provincial People's General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
6 Department of Epidemiology and Biostatistics, University of Texas Health San Antonio, Laredo, TX, United States.
7 School of Kinesiology, Shanghai University of Sport, Shanghai, China.
8 The Sports and Health Promotion International Collaboration and Innovation Center for People with Disability, Guangzhou, China.
Conference/Journal: Front Oncol
Date published: 2022 Aug 5
Other: Volume ID: 12 , Pages: 807531 , Special Notes: doi: 10.3389/fonc.2022.807531. , Word Count: 244
The aim of the current study is to investigate the impact of Baduanjin, a traditional Chinese exercise, on quality of life and sleep quality in breast cancer survivors receiving aromatase inhibitor (AI) therapy.
A total of 72 breast cancer survivors who had received AI treatment for more3 than 6 months were enrolled in the current study using non-probability consecutive sampling procedure. Participants were randomly assigned in a 1:1 ratio to a 12-week Baduanjin exercise program or to a wait-list control group. The Baduanjin exercise group performed two 90-min supervised sessions per week. The primary outcomes were changes in quality of life measured by the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 (EORTC QLQ-C30) and in sleep quality evaluated using the Pittsburgh Sleep Quality Index (PSQI).
A total of 68 participants completed the trial (Baduanjin exercise group: n = 33; control group: n = 35). Baseline values for quality of life did not differ between groups. Both global quality of life and physical functioning scores increased significantly by 12.39 (P < 0.001) and 8.48 (P < 0.001) in the Baduanjin exercise group compared with those in the control. Overall PSQI score also decreased by 4.85 (P < 0.001) in the Baduanjin exercise group, whereas it increased by 0.34 in the control group.
Baduanjin exercise training led to improvement in the quality of life and sleep quality of breast cancer patients undergoing AI therapy.
Keywords: Baduanjin exercise; aromatase inhibitor therapy; breast cancer survivors; quality of life; sleep quality.
PMID: 35992855 PMCID: PMC9388824 DOI: 10.3389/fonc.2022.807531