Author: A L Goldberger1
1 Harvard Medical School, Boston, MA 02215.
2 Harvard Med Sch, Boston, Cardiovascular Div
Conference/Journal: News Physiol Sci
Date published: 1991 Apr 1
Other: Volume ID: 6 , Pages: 87-91 , Special Notes: doi: 10.1152/physiologyonline.19220.127.116.11. , Word Count: 54
Limits to the usefulness of homeostasis as a guiding physiological principle are revealed by new mechanisms derived from study of nonlinear systems that generate a type of variability called chaos. Loss of complex physiological variability may occur in certain pathological conditions including heart rate dynamics before sudden death and with aging.
PMID: 11537649 DOI: 10.1152/physiologyonline.1918.104.22.168