Effectiveness of Yoga Lifestyle on Lipid Metabolism in a Vulnerable Population-A Community Based Multicenter Randomized Controlled Trial

Author: Raghuram Nagarathna1, Saurabh Kumar2, Akshay Anand2,3,4, Ishwara N Acharya5, Amit Kumar Singh1, Suchitra S Patil1, Ramesh H Latha6, Purnima Datey7, Hongasandra Ramarao Nagendra1
1 Swami Vivekananda Yoga Anusandhana Samsthana (S-VYASA), Bengaluru 560105, India.
2 Neuroscience Research Lab, Department of Neurology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India.
3 Centre for Mind Body Medicine, PGIMER, Chandigarh 160012, India.
4 Centre for Cognitive Science and Phenomenology, Panjab University, Chandigarh 160014, India.
5 Central Council for Research in Yoga & Naturopathy (CCRYN), Delhi 110058, India.
6 Yoga Clinic, Bhopal 462026, India.
7 Arogya Rasahara Kendra, Bhopal 462024, India.
Conference/Journal: Medicines (Basel)
Date published: 2021 Jul 13
Other: Volume ID: 8 , Issue ID: 7 , Pages: 37 , Special Notes: doi: 10.3390/medicines8070037. , Word Count: 229

Background: Dyslipidemia poses a high risk for cardiovascular disease and stroke in Type 2 diabetes (T2DM). There are no studies on the impact of a validated integrated yoga lifestyle protocol on lipid profiles in a high-risk diabetes population. Methods: Here, we report the results of lipid profile values of 11,254 (yoga 5932 and control 5322) adults (20-70 years) of both genders with high risk (≥60 on Indian diabetes risk score) for diabetes from a nationwide rural and urban community-based two group (yoga and conventional management) cluster randomized controlled trial. The yoga group practiced a validated integrated yoga lifestyle protocol (DYP) in nine day camps followed by daily one-hour practice. Biochemical profiling included glycated hemoglobin and lipid profiles before and after three months. Results: There was a significant difference between groups (p < 0.001 ANCOVA) with improved serum total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein in the yoga group compared to the control group. Further, the regulatory effect of yoga was noted with a significant decrease or increase in those with high or low values of lipids, respectively, with marginal or no change in those within the normal range. Conclusion: Yoga lifestyle improves and regulates (lowered if high, increased if low) the blood lipid levels in both genders of prediabetic and diabetic individuals in both rural and urban Indian communities.

Keywords: diabetes; diabetes yoga protocol; dyslipidemia; lipid regulation; prediabetes.

PMID: 34357153 PMCID: PMC8303653 DOI: 10.3390/medicines8070037