Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases

Author: B K Pedersen1, B Saltin2
1 The Centre of Inflammation and Metabolism and The Center for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
2 The Copenhagen Muscle Research Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Conference/Journal: Scand J Med Sci Sports
Date published: 2015 Dec 1
Other: Volume ID: 25 Suppl 3 , Pages: 1-72 , Special Notes: doi: 10.1111/sms.12581. , Word Count: 140

This review provides the reader with the up-to-date evidence-based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia); neurological diseases (dementia, Parkinson's disease, multiple sclerosis); metabolic diseases (obesity, hyperlipidemia, metabolic syndrome, polycystic ovarian syndrome, type 2 diabetes, type 1 diabetes); cardiovascular diseases (hypertension, coronary heart disease, heart failure, cerebral apoplexy, and claudication intermittent); pulmonary diseases (chronic obstructive pulmonary disease, asthma, cystic fibrosis); musculo-skeletal disorders (osteoarthritis, osteoporosis, back pain, rheumatoid arthritis); and cancer. The effect of exercise therapy on disease pathogenesis and symptoms are given and the possible mechanisms of action are discussed. We have interpreted the scientific literature and for each disease, we provide the reader with our best advice regarding the optimal type and dose for prescription of exercise.

Keywords: cancer; cardiovascular; neuropsychiatric; physical activity; physical training; type 2 diabetes.

PMID: 26606383 DOI: 10.1111/sms.12581