Effects of music-based movement therapy on motor function, balance, gait, mental health, and quality of life for patients with Parkinson's disease: A systematic review and meta-analysis

Author: Zonglei Zhou1, Ruzhen Zhou2, Wen Wei1, Rongsheng Luan1, Kunpeng Li3
1 West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
2 Department of Anorectal Surgery, Changhai Hospital of Shanghai, Shanghai, China.
3 Department of Neurorehabilitation, Shanghai Second Rehabilitation Hospital, Shanghai, China.
Conference/Journal: Clin Rehabil
Date published: 2021 Jul 1
Other: Volume ID: 35 , Issue ID: 7 , Pages: 937-951 , Special Notes: doi: 10.1177/0269215521990526. , Word Count: 223

To conduct a systematic review evaluating the effects of music-based movement therapy on motor function, balance, gait, mental health, and quality of life among individuals with Parkinson's disease.

Data sources:
A systematic search of PubMed, Embase, Cochrane Library, Web of Science, PsycINFO, CINAHL, and Physiotherapy Evidence Database was carried out to identify eligible papers published up to December 10, 2020.

Review methods:
Literature selection, data extraction, and methodological quality assessment were independently performed by two investigators. Publication bias was determined by funnel plot and Egger's regression test. "Trim and fill" analysis was performed to adjust any potential publication bias.

Seventeen studies involving 598 participants were included in this meta-analysis. Music-based movement therapy significantly improved motor function (Unified Parkinson's Disease Rating Scale motor subscale, MD = -5.44, P = 0.002; Timed Up and Go Test, MD = -1.02, P = 0.001), balance (Berg Balance Scale, MD = 2.02, P < 0.001; Mini-Balance Evaluation Systems Test, MD = 2.95, P = 0.001), freezing of gait (MD = -2.35, P = 0.039), walking velocity (MD = 0.18, P < 0.001), and mental health (SMD = -0.38, P = 0.003). However, no significant effects were observed on gait cadence, stride length, and quality of life.

The findings of this study show that music-based movement therapy is an effective treatment approach for improving motor function, balance, freezing of gait, walking velocity, and mental health for patients with Parkinson's disease.

Keywords: Music-based movement therapy; Parkinson’s disease; meta-analysis; rehabilitation.

PMID: 33517767 DOI: 10.1177/0269215521990526