Exercise, cognition, and the aging brain

Author: Arthur F Kramer1, Kirk I Erickson, Stanley J Colcombe
Affiliation:
1 Beckman Institute, University of Illinois, 405 North Mathews Ave., Urbana, 61801, USA. akramer@s.psych.uiuc.edu
Conference/Journal: J Appl Physiol (1985)
Date published: 2006 Oct 1
Other: Volume ID: 101 , Issue ID: 4 , Pages: 1237-42 , Special Notes: doi: 10.1152/japplphysiol.00500.2006. , Word Count: 107


We provide a brief review of the literature on exercise effects on brain and cognition. To this end, we focus on both prospective and retrospective human epidemiological studies that have examined the influence of exercise and physical activity on cognition and dementia. We then examine the relatively small set of human randomized clinical trials that have, for the most part, focused on exercise training effects on cognition. Next, we discuss animal research that has examined the molecular, cellular, and behavioral effects of exercise training. Finally, we conclude with a summary and brief discussion of important future directions of research on fitness cognition and brain.


PMID: 16778001 DOI: 10.1152/japplphysiol.00500.2006

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