Author: Jinke Huang1, Xiaohui Qin2, Min Shen3, Yanjuan Xu1, Yong Huang4
1 The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
2 Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
3 Department of Neurology, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, China.
4 School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Conference/Journal: Front Cardiovasc Med
Date published: 2021 Mar 18
Other: Volume ID: 8 , Pages: 589267 , Special Notes: doi: 10.3389/fcvm.2021.589267. , Word Count: 276
Background: Tai chi (TC) is a popular form of exercise among adults with chronic heart failure (CHF), yet services are greatly underutilized. The aim of the current study was to identify and summarize the existing evidence and to systematically determine the clinical effectiveness of Tai Chi in the management of CHF using a systematic overview. Methods: Both English and Chinese databases were searched for systematic reviews (SRs)/meta-analyses (MAs) on TC for CHF from their inception to June 2020. The methodological quality, reporting quality, and risk of bias of SRs/MAs were assessed using Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2), the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist, and Risk of Bias in Systematic reviews (ROBIS), respectively. The evidence quality of outcome measures was assessed by the Grades of Recommendations, Assessment, Development and Evaluation (GRADE). Results: Six SRs/MAs using a quantitative synthesis to assess various outcomes of TC in CHF were included in this overview. The methodological quality, reporting quality and risk of bias of the SRs/MAs and the evidence quality of the outcome measures are generally unsatisfactory. The limitations of the past SRs/MAs included the lack of either the protocol or registration, the list of excluded studies, and the computational details of meta-analysis were inadequately reported. The critical problems were that qualitative data synthesis relied on trials with small sample sizes and critical low quality. Conclusions: TC may be a promising complementary treatment for CHF. However, further rigorous and comprehensive SRs/MAs and RCTs are required to provide robust evidence for definitive conclusions.
Keywords: AMSTAR-2; GRADE; PRISMA; ROBIS; Tai Chi; heart failure; overview.
PMID: 33816570 PMCID: PMC8012482 DOI: 10.3389/fcvm.2021.589267