New approaches for treating atrial fibrillation: Focus on autonomic modulation
Author: Daniel Sohinki1, Stavros Stavrakis2
Affiliation:
1 Department of Cardiology, Augusta University Medical Center, Augusta, GA, United States.
2 Department of Cardiology, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd., Suite 5400, Oklahoma, OK, United States; Heart Rhythm Institute, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States. Electronic address: stavros-stavrakis@ouhsc.edu.
Conference/Journal: Trends Cardiovasc Med
Date published: 2020 Oct 1
Other:
Volume ID: 30 , Issue ID: 7 , Pages: 433-439 , Special Notes: doi: 10.1016/j.tcm.2019.10.009. , Word Count: 131
Atrial fibrillation (AF) is a rapidly growing clinical problem in routine practice, both for cardiologists as well as general practitioners. Current therapies aimed at the management of AF include anti-arrhythmic drug therapy and catheter ablation. These therapies have a number of limitations and risks, and have disappointing long-term efficacy in maintaining sinus rhythm and improving hard clinical outcomes. Because of this, there is growing interest in pursuing alternative management strategies in patients with AF. This review seeks to highlight emerging AF therapies, with a specific focus on several modalities aimed at modulation of the autonomic nervous system. These therapies have shown promise in early pre-clinical and clinical trials, and represent exciting alternatives to standard AF treatment.
Keywords: Atrial fibrillation; Autonomic modulation.
PMID: 31708408 PMCID: PMC7190441 (available on 2021-10-01) DOI: 10.1016/j.tcm.2019.10.009
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