Author: Zhang Q1, Gao X2, Liu S2, Yu L1, Zhu J1, Qiu S2
1First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang.
2The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), China.
Conference/Journal: Medicine (Baltimore).
Date published: 2020 May
Other: Volume ID: 99 , Issue ID: 19 , Pages: e20092 , Special Notes: doi: 10.1097/MD.0000000000020092. , Word Count: 184
OBJECTIVE: The aim of this systematic review was to evaluate the effect of therapies for cognitive impairment on patients' perceived cognitive function in breast cancer survivors with chemotherapy-related cognitive impairment.
METHOD: A literature search of PubMed, Embase, and the Cochrane Library was conducted up to April 2019. Search terms included breast cancer, chemotherapy, and cognitive impairment.
RESULT: Six randomized controlled trials with a total of 305 patients were included in this review. A total of 6 randomized controlled trials using various treatments (Tibetan sound meditation, donepezil, memory and attention adaptation training, aerobic exercise, acupuncture, Qigong) for chemotherapy-related cognitive impairment met the eligibility criteria and were included. This review showed that meditative interventions (Tibetan sound meditation, Qigong) and cognitive therapy (memory and attention adaptation training) may partially improve some aspects of patients' perceived (self-reported) cognitive functioning, particularly patients' perceived cognitive impairment and ability.
CONCLUSION: In this systematic review, the results showed that meditative interventions (Tibetan sound meditation, Qigong) and cognitive therapy (memory and attention adaptation training) may be optional therapies. We hope to have more randomized controlled trials to support this result in the future.
PMID: 32384481 DOI: 10.1097/MD.0000000000020092