Collateral benefits of studying the vagus nerve in bioelectronic medicine.
Author: Pavlov VA1,2
Affiliation:
11Center for Biomedical Science and Bioelectronic Medicine, The Feinstein Institute for Medical Research, Northwell Health System, Manhasset, NY 11030 USA.
2Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11550 USA.
Conference/Journal: Bioelectron Med.
Date published: 2019 May 16
Other:
Volume ID: 5 , Pages: 5 , Special Notes: doi: 10.1186/s42234-019-0021-3. eCollection 2019. , Word Count: 116
Studies on the role of the vagus nerve in the regulation of immunity and inflammation have contributed to current preclinical and clinical efforts in bioelectronic medicine. In parallel, this research has generated new insights into the cellular and molecular mechanisms underlying the immunoregulatory functions of the vagus nerve within the inflammatory reflex. The vagus nerve and other cellular components of the inflammatory reflex are implicated in the regulation of bleeding, cancer, obesity, blood pressure, viral infections and other conditions. This collateral benefit broadens scientific horizons and provides new rationale for technological advances and therapeutic implications.
© The Author(s) 2019.
KEYWORDS: Bioelectronic medicine; Cholinergic; Cytokines; Inflammation; Inflammatory diseases; Vagus nerve
PMID: 32232096 PMCID: PMC7098239 DOI: 10.1186/s42234-019-0021-3
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