The Beneficial Effects of Mind-body Exercises for People with Mild Cognitive Impairment: A Systematic Review with Meta-Analysis.

Author: Zou L1, Loprinzi PD2, Yeung AS3, Zeng N4, Huang T5
1Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address:
2Exercise & Memory Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS 38677, USA.
3Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical, School, Boston, MA 02114, USA.
4Department of Food Science and Human Nutrition, Colorado State University, CO 80523, USA.
5Department of Physical Education, Shanghai Jiaotong University, Shanghai, 200000, China.
Conference/Journal: Arch Phys Med Rehabil.
Date published: 2019 Apr 12
Other: Pages: S0003-9993(19)30239-4 , Special Notes: doi: 10.1016/j.apmr.2019.03.009. [Epub ahead of print] , Word Count: 228

OBJECTIVE: To objectively evaluate the most common forms of mind body exercise (MBE) (Tai Chi, Yoga, and Qigong) on cognitive function among people with MCI.

DATA SOURCES: We searched six electronic databases (Scopus, PubMed, PsycINFO, WanFang, Web of Science, and CNKI) from inception until September, 2018.

STUDY SELECTION: Nine randomized controlled trials and three non-randomized controlled trials were included for meta-analysis.

DATA EXTRACTION: Two researchers independently performed the literature searches, study selection, data extraction, and methodological quality assessment using the revised Physiotherapy Evidence Database (PEDro) scale.

DATA SYNTHESIS: The pooled effect size (standardized mean difference, SMD) was calculated while random-effect model was selected. Overall results of the meta-analysis (N = 1298 people with MCI) indicated that MBE significantly improved attention (SMD = 0.39, 95% CI 0.07 to 0.71, p = 0.02, I2 = 31.6%, N = 245), short-term memory (SMD = 0.74, 95% CI 0.57 to 0.90, p < 0.001, I2 = 0%, N = 861), executive function (SMD = -0.42, 95% CI -0.63 to -0.21, p < 0.001, I2 = 38.54%, N = 701), visual-spatial/executive function (SMD = 0.35, 95% CI 0.07 to 0.64, p < 0.05, I2 = 0%, N = 285), and global cognitive function (SMD = 0.36, 95% CI 0.2 to 0.52, p < 0.001, I2 = 15.12%, N = 902). However, the significant positive effect on cognitive processing speed was not observed following MBE interventions (SMD = 0.31, 95% CI -0.01 to 0.63, p = 0.054, I2 = 28.66%, N = 233).

CONCLUSIONS: Study findings of this meta-analysis suggest that MBE have the potential to improve various cognitive functions in people with MCI.

Copyright © 2019. Published by Elsevier Inc.

KEYWORDS: MCI; Mind-body exercise; Qigong; Tai Chi; Yoga; mild cognitive impairment

PMID: 30986409 DOI: 10.1016/j.apmr.2019.03.009