Author: Boerema AS1,2, Heesterbeek M2, Boersma SA1,2, Schoemaker R2, de Vries EFJ1, van Heuvelen MJG3, Van der Zee EA2
1Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
2Groningen Institute for Evolutionary Life Sciences (GELIFES), Molecular Neurobiology, University of Groningen, Groningen, the Netherlands.
3Center for Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Conference/Journal: Dose Response.
Date published: 2018 Dec 4
Other: Volume ID: 16 , Issue ID: 4 , Pages: 1559325818811756 , Special Notes: doi: 10.1177/1559325818811756. eCollection 2018 Oct-Dec. , Word Count: 203
The biological consequences of mechanical whole body vibration (WBV) on the brain are not well documented. The aim of the current study was to further investigate the effects of a 5-week WBV intervention on brain functions. Mice (C57Bl/6J males, age 15 weeks) were exposed to 30 Hz WBV sessions (10 minutes per day, 5 days per week, for a period of 5 weeks; n = 10). Controls received the same intervention without the actual vibration (n = 10). Humans (both genders, age ranging from 44-99 years) were also exposed to daily sessions of 30 Hz WBV (4 minutes per day, 4 days per week, for a period of 5 weeks; n = 18). Controls received the same protocol using a 1 Hz protocol (n = 16). Positron emission tomography imaging was performed in the mice, and revealed that glucose uptake was not changed as a consequence of the 5-week WBV intervention. Whole body vibration did, however, improve motor performance and reduced arousal-induced home cage activity. Cognitive tests in humans revealed a selective improvement in the Stroop Color-Word test. Taken together, it is concluded that WBV is a safe intervention to improve brain functioning, although the subtle effects suggest that the protocol is as yet suboptimal.
KEYWORDS: behavioral arousal; brain glucose metabolism; executive functions; motor performance
PMID: 30574028 PMCID: PMC6299320 DOI: 10.1177/1559325818811756