Mindfulness-Based Interventions for Adults Living with HIV/AIDS: A Systematic Review and Meta-analysis.

Author: Scott-Sheldon LAJ1,2,3, Balletto BL4, Donahue ML4, Feulner MM4, Cruess DG5, Salmoirago-Blotcher E4,6,7, Wing RR4,8, Carey MP4,8,9
Affiliation:
1Centers for Behavioral and Preventive Medicine, The Miriam Hospital, CORO Building, Suite 309, 164 Summit Avenue, Providence, RI, 02906, USA. lori_scott-sheldon@brown.edu.
2Department of Psychiatry and Human Behavior, Alpert School of Medicine, Brown University, Providence, RI, USA. lori_scott-sheldon@brown.edu.
3Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA. lori_scott-sheldon@brown.edu.
4Centers for Behavioral and Preventive Medicine, The Miriam Hospital, CORO Building, Suite 309, 164 Summit Avenue, Providence, RI, 02906, USA.
5Department of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
6Department of Medicine, Alpert School of Medicine, Brown University, Providence, RI, USA.
7Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
8Department of Psychiatry and Human Behavior, Alpert School of Medicine, Brown University, Providence, RI, USA.
9Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
Conference/Journal: AIDS Behav.
Date published: 2018 Jul 27
Other: Special Notes: doi: 10.1007/s10461-018-2236-9. [Epub ahead of print] , Word Count: 175

This meta-analysis examined the effects of mindfulness-based interventions (MBIs) on stress, psychological symptoms, and biomarkers of disease among people living with HIV/AIDS (PLWHA). Comprehensive searches identified 16 studies that met the inclusion criteria (N = 1059; M age = 42 years; 20% women). Participants had been living with HIV for an average of 8 years (range = < 1-20 years); 65% were currently on antiretroviral therapy. Between-group analyses indicated that depressive symptoms were reduced among participants receiving the MBIs compared to controls (d+ = 0.37, 95% CI 0.03, 0.71). Within-group analyses showed reductions in psychological symptoms (i.e., less anxiety, fewer depressive symptoms) and improved quality of life over time among MBI participants (d+s = 0.40-0.85). No significant changes were observed for immunological outcomes (i.e., CD4 counts) between- or within-groups. MBIs may be a promising approach for reducing psychological symptoms and improving quality of life among PLWHA. Studies using stronger designs (i.e., randomized controlled trials) with larger sample sizes and longer follow-ups are needed to clarify the potential benefits of MBIs for PLWHA.

KEYWORDS: HIV; Intervention; Meta-analysis; Mindfulness; Systematic review

PMID: 30054765 DOI: 10.1007/s10461-018-2236-9

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