A systematic review of randomized trials of mind-body interventions for PTSD.

Author: Niles BL1, Mori DL2, Polizzi C3, Pless Kaiser A1, Weinstein ES3, Gershkovich M4, Wang C5
Affiliation:
1National Center for PTSD and Boston University School of Medicine.
2VA Boston Healthcare System and Boston University School of Medicine.
3National Center for PTSD.
4VA Boston Healthcare System.
5Center for Complementary and Integrative Medicine at Tufts University School of Medicine.
Conference/Journal: J Clin Psychol.
Date published: 2018 May 10
Other: Special Notes: doi: 10.1002/jclp.22634. [Epub ahead of print] , Word Count: 161


OBJECTIVE: To systematically review outcomes from randomized controlled trials (RCTs) of mind-body treatments for PTSD.

METHODS: Inclusion criteria based on guidelines for assessing risk of bias were used to evaluate articles identified through electronic literature searches.

RESULTS: Twenty-two RCTs met inclusion standards. In most of the nine mindfulness and six yoga studies, significant between-group effects were found indicating moderate to large effect size advantages for these treatments. In all seven relaxation RCT's, relaxation was used as a control condition and five studies reported significant between-group differences on relevant PTSD outcomes in favor of the target treatments. However, there were large within-group symptom improvements in the relaxation condition for the majority of studies.

CONCLUSIONS: Although many studies are limited by methodologic weaknesses, recent studies have increased rigor and, in aggregate, the results for mindfulness, yoga, and relaxation are promising. Recommendations for design of future mind-body trials are offered.

© 2018 Wiley Periodicals, Inc.

KEYWORDS: PTSD; mind-body; randomized controlled trial; systematic review

PMID: 29745422 DOI: 10.1002/jclp.22634

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