Author: Zilov VG1, Subbotina TI2, Yashin AA2, Khadartsev AA3, Ivanov DV2
1I. M. Sechenov First Moscow State Medical University, the Ministry of Health of Russia, Moscow, Russia.
2Tula State University, Tula, Russia.
3Tula State University, Tula, Russia. email@example.com.
Conference/Journal: Bull Exp Biol Med.
Date published: 2018 Mar 26
Other: Special Notes: doi: 10.1007/s10517-018-4059-0. [Epub ahead of print] , Word Count: 157
Experimental validation of the method for regulation of stem cell proliferation and differentiation is carried out. The method consists in exposure to ultrahigh frequency electromagnetic radiation, modulated by infralow frequencies with variable parameters. A specially designed programmer, setting up the parameters of exposure, is connected to the source of radiation. The zones of anatomical location of the red bone marrow of rats were exposed for 15 min to the amplitude-modulated electromagnetic radiation of ultrahigh frequency range. The parameters of exposure were determined in previous studies. The red bone marrow was collected from the sternum and head of the femur. The cellular composition of the red bone marrow was evaluated 1, 2, 3, and 6 days after the exposure. The optimal therapeutic mode of irradiation was then chosen, leading to stem cell activation with subsequent proliferation and differentiation into mature red bone marrow cells.
KEYWORDS: amplitude modulation; electromagnetic ultrahigh frequency radiation; implantation; red bone marrow; stem cells
PMID: 29577191 DOI: 10.1007/s10517-018-4059-0