Author: Lee AC1, Harvey WF2, Price LL3, Morgan LPK4, Morgan NL5, Wang C6
Affiliation:
1Center for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: Alee10@Tuftsmedicalcenter.org.
2Center for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: WHarvey@Tuftsmedicalcenter.org.
3Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA; Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, USA. Electronic address: Lprice1@Tuftsmedicalcenter.org.
4Department of Psychology, University of Massachusetts Boston, Boston, MA, USA; I Ola Lahui Rural Hawai'i Behavioral Health, Honolulu, HI, USA. Electronic address: lucas.morgan@gmail.com.
5Center for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA; Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA. Electronic address: nani.loui@gmail.com.
6Center for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: CWang2@Tuftsmedicalcenter.org.
Conference/Journal: Osteoarthritis Cartilage.
Date published: 2017 Jun
Other:
Volume ID: 25 , Issue ID: 6 , Pages: 824-831 , Special Notes: doi: 10.1016/j.joca.2016.06.017. Epub 2016 Jun 24. , Word Count: 287
OBJECTIVE: Previous studies suggest that higher mindfulness is associated with less pain and depression. However, the role of mindfulness has never been studied in knee osteoarthritis (OA). We evaluate the relationships between mindfulness and pain, psychological symptoms, and quality of life in knee OA.
METHOD: We performed a secondary analysis of baseline data from our randomized comparative trial in participants with knee OA. Mindfulness was assessed using the Five Facet Mindfulness Questionnaire (FFMQ). We measured pain, physical function, quality of life, depression, stress, and self-efficacy with commonly-used patient-reported measures. Simple and multivariable regression models were utilized to assess associations between mindfulness and health outcomes. We further tested whether mindfulness moderated the pain-psychological outcome associations.
RESULTS: Eighty patients were enrolled (60.3 ± 10.3 years; 76.3% female, body mass index: 33.0 ± 7.1 kg/m2). Total mindfulness score was associated with mental (beta = 1.31, 95% CI: 0.68, 1.95) and physical (beta = 0.69, 95% CI:0.06, 1.31) component quality of life, self-efficacy (beta = 0.22, 95% CI:0.07, 0.37), depression (beta = -1.15, 95% CI:-1.77, -0.54), and stress (beta = -1.07, 95% CI:-1.53, -0.60). Of the five facets, the Describing, Acting-with-Awareness, and Non-judging mindfulness facets had the most associations with psychological health. No significant association was found between mindfulness and pain or function (P = 0.08-0.24). However, we found that mindfulness moderated the effect of pain on stress (P = 0.02).
CONCLUSION: Mindfulness is associated with depression, stress, self-efficacy, and quality of life among knee OA patients. Mindfulness also moderates the influence of pain on stress, which suggests that mindfulness may alter the way one copes with pain. Future studies examining the benefits of mind-body therapy, designed to increase mindfulness, for patients with OA are warranted.
Copyright © 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
KEYWORDS: Chronic pain; Mindfulness; Osteoarthritis; Psychological stress
PMID: 27349461 PMCID: PMC5183521 [Available on 2018-06-01] DOI: 10.1016/j.joca.2016.06.017
