Author: Lai CC1, Tu YK2, Wang TG1, Huang YT2, Chien KL2
1Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
2Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Conference/Journal: Age Ageing.
Date published: 2018 Feb 17
Other: Special Notes: doi: 10.1093/ageing/afy009. [Epub ahead of print] , Word Count: 251
Background: A variety of different types of exercise are promoted to improve muscle strength and physical performance in older people.
Objective: We aimed to determine the relative effects of resistance training, endurance training and whole-body vibration on lean body mass, muscle strength and physical performance in older people.
Design: A systematic review and network meta-analysis.
Subjects: Adults aged 60 and over.
Methods: Evidence from randomised controlled trials of resistance training, endurance training and whole-body vibration were combined. The effects of exercise interventions on lean body mass, muscle strength and physical performance were evaluated by conducting a network meta-analysis to compare multiple interventions and usual care. Risk of bias of included studies was assessed using the Cochrane Collaboration's tool. A meta-regression was performed to assess potential effect modifiers.
Results: Data were obtained from 30 trials involving 1,405 participants (age range: 60-92 years). No significant differences were found between the effects of exercise or usual care on lean body mass. Resistance training (minimum 6 weeks duration) achieved greater muscle strength improvement than did usual care (12.8 kg; 95% confidence interval [CI]: 8.5-17.0 kg). Resistance training and whole-body vibration were associated with greater physical performance improvement compared with usual care (2.6 times greater [95% CI: 1.3-3.9] and 2.1 times greater [95% CI: 0.5-3.7], respectively).
Conclusions: Resistance training is the most effect intervention to improve muscle strength and physical performance in older people. Our findings also suggest that whole-body vibration is beneficial for physical performance. However, none of the three exercise interventions examined had a significant effect on lean body mass.
PMID: 29471456 DOI: 10.1093/ageing/afy009