Yoga training modulates adipokines in adults with high-normal blood pressure and metabolic syndrome.

Author: Supriya R1, Yu AP2, Lee PH3, Lai CW1, Cheng KK1, Yau SY4, Chan LW1, Yung BY1, Siu PM2
1Department of Health Technology and Informatics.
2School of Public Health, Li Ka Shing, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
3School of Nursing.
4Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Conference/Journal: Scand J Med Sci Sports.
Date published: 2017 Dec 5
Other: Special Notes: doi: 10.1111/sms.13029. [Epub ahead of print] , Word Count: 269

OBJECTIVES: Metabolic syndrome (MetS) is associated with diabetes mellitus and cardiovascular diseases. Our previous study indicated that people with MetS showed a decrease in waist circumference and a decreasing trend in blood pressure after 1 year of yoga. This study investigated the effect of yoga on MetS people with high-normal blood pressure by exploring modulations in pro-inflammatory adipokines (leptin, chemerin, visfatin and plasminogen activator inhibitor-1 or PAI-1) and an anti-inflammatory adipokine (adiponectin).

DESIGN & METHODS: A total of 97 Hong Kong Chinese individuals aged 57.6 ± 9.1 years with MetS and high-normal blood pressure were randomly assigned to control (n = 45) and yoga groups (n = 52). Participants in the control group were not given any intervention but were contacted monthly to monitor their health status. Participants in the yoga group underwent a yoga training programme with three 1-hour yoga sessions weekly for 1 year. The participants' sera were harvested and assessed for adipokines. Generalized estimating equation (GEE) was used to examine the interaction effect between 1 year of time (pre vs. post) and intervention (control vs. yoga).

RESULTS: GEE analyses revealed significant interaction effects between 1-year of time and yoga intervention for the decreases in leptin and chemerin and the increase in adiponectin concentration in the sera examined.

CONCLUSION: These results demonstrated that 1 year of yoga training decreased pro-inflammatory adipokines and increased anti-inflammatory adipokine in adults with MetS and high-normal blood pressure. These findings support the beneficial role of yoga in managing MetS by favourably modulating adipokines. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.

KEYWORDS: Hypertension; Mind-body exercise; adipokine; high blood pressure; metabolic syndrome

PMID: 29205515 DOI: 10.1111/sms.13029