Whole-body vibration to prevent intensive care unit-acquired weakness: safety, feasibility, and metabolic response.

Author: Wollersheim T1,2, Haas K1, Wolf S3, Mai K2,4, Spies C1, Steinhagen-Thiessen E5, Wernecke KD1,6, Spranger J2,4,7, Weber-Carstens S8,9.
Author Information:
1Department of Anesthesiology and Operative Intensive Care Medicine, Campus Virchow Klinikum and Campus Mitte, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany.
2Berlin Institute of Health (BIH), Berlin, 13353, Germany.
3Department of Neurosurgery, Charité-Universitätsmedizin Berlin, Berlin, 13353, Germany.
4Department of Endocrinology, Diabetes and Nutrition, Charité-Universitätsmedizin Berlin, Berlin, 10177, Germany.
5Research Group on Geriatrics, Charité-Universitätsmedizin Berlin, Berlin, 13353, Germany.
6CRO SOSTANA GmbH Berlin, Berlin, 10318, Germany.
7DZHK (German Centre for Cardiovascular Research), partner site Charité Berlin, Berlin, 10177, Germany.
8Department of Anesthesiology and Operative Intensive Care Medicine, Campus Virchow Klinikum and Campus Mitte, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany. steffen.weber-carstens@charite.de.
9Berlin Institute of Health (BIH), Berlin, 13353, Germany. steffen.weber-carstens@charite.de.
Conference/Journal: Crit Care.
Date published: 2017 Jan 9
Other: Volume ID: 21 , Issue ID: 1 , Pages: 9 , Special Notes: doi: 10.1186/s13054-016-1576-y. , Word Count: 301


Abstract
BACKGROUND:
Intensive care unit (ICU)-acquired weakness in critically ill patients is a common and significant complication affecting the course of critical illness. Whole-body vibration is known to be effective muscle training and may be an option in diminishing weakness and muscle wasting. Especially, patients who are immobilized and not available for active physiotherapy may benefit. Until now whole-body vibration was not investigated in mechanically ventilated ICU patients. We investigated the safety, feasibility, and metabolic response of whole-body vibration in critically ill patients.
METHODS:
We investigated 19 mechanically ventilated, immobilized ICU patients. Passive range of motion was performed prior to whole-body vibration therapy held in the supine position for 15 minutes. Continuous monitoring of vital signs, hemodynamics, and energy metabolism, as well as intermittent blood sampling, took place from the start of baseline measurements up to 1 hour post intervention. We performed comparative longitudinal analysis of the phases before, during, and after intervention.
RESULTS:
Vital signs and hemodynamic parameters remained stable with only minor changes resulting from the intervention. No application had to be interrupted. We did not observe any adverse event. Whole-body vibration did not significantly and/or clinically change vital signs and hemodynamics. A significant increase in energy expenditure during whole-body vibration could be observed.
CONCLUSIONS:
In our study the application of whole-body vibration was safe and feasible. The technique leads to increased energy expenditure. This may offer the chance to treat patients in the ICU with whole-body vibration. Further investigations should focus on the efficacy of whole-body vibration in the prevention of ICU-acquired weakness.
TRIAL REGISTRATION:
Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients. ClinicalTrials.gov NCT01286610 . Registered 28 January 2011.
KEYWORDS:
Intensive care unit-acquired weakness; Metabolism; Mobilization; Muscle wasting; Physiotherapy; Whole-body vibration
PMID: 28065165 PMCID: PMC5220605 DOI: 10.1186/s13054-016-1576-y
[PubMed - in process] Free PMC Article

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