Mechanisms and therapeutic applications of electromagnetic therapy in Parkinson's disease.
Author: Vadalà M1, Vallelunga A2, Palmieri L3, Palmieri B4, Morales-Medina JC5, Iannitti T6.
Affiliation:
1Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy. mary.vadala@gmail.com. 2Department of Medicine and Surgery, Centre for Neurodegenerative Diseases (CEMAND), University of Salerno, Salerno, Italy. vallelungaannamaria@gmail.com. 3Department of Nephrology, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy. lucia.palmieri@gmail.com. 4Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy. palmieri@unimore.it. 5Centro de Investigación en Reproducción Animal, CINVESTAV-Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico. jmoralesm@cinvestav.mx. 6Department of Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK. tommaso.iannitti@gmail.com.
Conference/Journal: Behav Brain Funct.
Date published: 2015 Sep 7
Other:
Volume ID: 11 , Pages: 26 , Special Notes: doi: 10.1186/s12993-015-0070-z , Word Count: 114
Electromagnetic therapy is a non-invasive and safe approach for the management of several pathological conditions including neurodegenerative diseases. Parkinson's disease is a neurodegenerative pathology caused by abnormal degeneration of dopaminergic neurons in the ventral tegmental area and substantia nigra pars compacta in the midbrain resulting in damage to the basal ganglia. Electromagnetic therapy has been extensively used in the clinical setting in the form of transcranial magnetic stimulation, repetitive transcranial magnetic stimulation, high-frequency transcranial magnetic stimulation and pulsed electromagnetic field therapy which can also be used in the domestic setting. In this review, we discuss the mechanisms and therapeutic applications of electromagnetic therapy to alleviate motor and non-motor deficits that characterize Parkinson's disease.
PMID: 26347217
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