Ultra-weak Delayed Luminescence in cancer research: A review of the results by the ARETUSA equipment.
Author: Scordino A1, Baran I2, Gulino M3, Ganea C2, Grasso R4, Niggli JH5, Musumeci F6.
Affiliation:
1Physics and Astronomy Department, University of Catania, Catania, Italy; National Southern Laboratories, National Nuclear Physics Institute, Catania, Italy. Electronic address: scordino@lns.infn.it. 2Dept. of Biophysics, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. 3Engineering and Architecture Faculty, "Kore" University of Enna, Enna, Italy; National Southern Laboratories, National Nuclear Physics Institute, Catania, Italy. 4National Southern Laboratories, National Nuclear Physics Institute, Catania, Italy. 5BioFoton AG, Treyvaux, Switzerland. 6Physics and Astronomy Department, University of Catania, Catania, Italy; National Southern Laboratories, National Nuclear Physics Institute, Catania, Italy.
Conference/Journal: J Photochem Photobiol B.
Date published: 2014 May 20
Other:
Pages: S1011-1344(14)00148-1. , Special Notes: doi: 10.1016/j.jphotobiol.2014.03.027 , Word Count: 131
Abstract
The study of the photoinduced ultraweak photon emission in the optical wavelength range, namely the Delayed Luminescence, from human cells and tissues has an increasingly growing interest in view of its possible application in optical biopsy. Due to the low level, dedicated experimental set-up are necessary to reveal such photoluminescence signal. The paper reviews the results obtained in the field of cancer research, by using the experimental equipment for fast ultraweak luminescence analysis ARETUSA developed at the National Southern Laboratories of the National Nuclear Physics Institute (LNS-INFN), in Catania, Italy. Delayed Luminescence signals from normal and cancer cells are compared and the relationship between Delayed Luminescence and apoptosis is investigated.
Copyright © 2014 Elsevier B.V. All rights reserved.
KEYWORDS:
Apoptosis; Cancer diagnosis; Leukemia treatments; Modelling data; Photon detection; Ultraweak luminescence
PMID: 24912405
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