Are Short Telomeres Hallmarks of Cancer Recurrence?

Author: Shay JW.
Affiliation:
Cell Biology, The University of Texas Southwestern Medical Center at Dallas.
Conference/Journal: Clin Cancer Res.
Date published: 2013 Dec 23
Other: Word Count: 49

Exposure to radiation and some chemotherapeutic agents is associated with an increased risk of developing second cancers. Short telomeres are almost universally associated with malignant cancer progression. An outstanding question is if inherited short telomeres or therapy related telomere shortening is a biomarker of developing second malignant neoplasms.
PMID: 24366690

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