A randomized controlled trial of mindfulness-based stress reduction to manage affective symptoms and improve quality of life in gay men living with HIV.

Author: Gayner B, Esplen MJ, Deroche P, Wong J, Bishop S, Kavanagh L, Butler K.
Affiliation: Clinic for HIV-Related Concerns, Department of Psychiatry, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, 600 University Ave., Rm. 965A, Toronto, ON, M5G 1X5, Canada, bgayner@mtsinai.on.ca.
Conference/Journal: J Behav Med.
Date published: 2011 May 20
Other: Word Count: 140

To determine whether MBSR groups would help gay men living with HIV improve psychosocial functioning and increase mindfulness compared to treatment-as-usual (TAU). Methods: 117 participants were randomized 2:1 to MBSR or TAU. No new psychosocial or psychopharmacological interventions were initiated within 2 months of baseline. Standardized questionnaires were administered pre-, postintervention and at 6 months. An intent-to-treat analysis found significant benefits of MBSR: at post-intervention and 6 months follow up, MBSR participants had significantly lower avoidance in IES and higher positive affect compared to controls. MBSR participants developed more mindfulness as measured by the Toronto Mindfulness Scale (TMS) including both TMS subscales, curiosity and decentering, at 8-week and 6 months. For the sample as a whole, increase in mindfulness was significantly correlated with reduction in avoidance, higher positive affect and improvement in depression at 6 months. MBSR has specific and clinically meaningful effects in this population.

PMID: 21597980