Author: Ming-Gui Chen1, Fangfang Wang1, Lixia Huang1, Tingjie Qi1, Hanhua Guo1, Rui-Xiang Zeng1, Xiaoyan Li1, Haizhen Chen1, Min-Zhou Zhang1, Liheng Guo#2, Xiaoxuan Zhang#3
Affiliation: <sup>1</sup> Intensive Care Unit, The Second Clinical College of Guangzhou University of Chinese Medicine, No 111 Dade Road, Guangzhou, 510120, China.
<sup>2</sup> Intensive Care Unit, The Second Clinical College of Guangzhou University of Chinese Medicine, No 111 Dade Road, Guangzhou, 510120, China. guolh782@163.com.
<sup>3</sup> Intensive Care Unit, The Second Clinical College of Guangzhou University of Chinese Medicine, No 111 Dade Road, Guangzhou, 510120, China. zhxiaoxuan2003@163.com.
Conference/Journal: BMC Complement Med Ther
Date published: 2024 Sep 6
Other:
Volume ID: 24 , Issue ID: 1 , Pages: 330 , Special Notes: doi: 10.1186/s12906-024-04626-8. , Word Count: 319
Background:
For patients with sepsis receiving non-invasive ventilation (NIV), early rehabilitation is crucial. The Sitting Baduanjin (SBE) is an efficient early rehabilitation exercise suitable for bed patients. There is no consensus about the effect of SBE on the early rehabilitation of septic patients with NIV. This study focused on how the SBE affected the early rehabilitation of sepsis patients with NIV.
Methods:
96 sepsis patients with NIV were randomly assigned to either an Baduanjin group that received the SBE based on the routine rehabilitation exercise (n = 48) or a control group (n = 48) that received routine rehabilitation exercise. The primary outcome was the Medical Research Council(MRC)score, and the Barthel Index score, the duration of NIV, length of ICU stay, length of total stay, hospitalization expense as secondary outcomes.
Results:
A total of 245 sepsis patients were screened, with 96 randomly assigned. The study was completed by 90 patients out of the 96 participants.Results revealed that the MRC score increased in both groups, but the improvement of muscle strength in Baduanjin group was more obvious, with statistical significance (p < 0.001).There was statistically significantly difference between the two groups in Barthel Index at the day of transfer out of ICU(P = 0.028).The patients in the Baduanjin group had an average reduction of 24.09 h in the duration of NIV and 3.35 days in total length of hospital stay compared with the control group (p < 0.05).Of note, the Baduanjin group had significantly reduction the total hospitalization expense. No serious adverse events occurred during the intervention period.
Conclusions:
In patients with sepsis, the SBE appears to improve muscle strength and activities of daily living (ADL), and lowed the duration of NIV, the length of the total stay, and the hospitalization expense.
Trial registration:
The study registered on the Chinese Clinical Trial Registry ( www.chictr.org.cn ), Clinical Trials identifier ChiCTR1800015011 (28/02/2018).
Keywords: Early rehabilitation; Non-invasive ventilation; Sepsis; The sitting baduanjin.
PMID: 39243078 PMCID: PMC11378565 DOI: 10.1186/s12906-024-04626-8