Author: Qingyuan Zhang#1,2, Xiaogang Xu#1, Qianyan Wu1, Jingwen Zhang1, Shenghe Huang1, Lin Wu1, Minping Tian3, Delin Zhang1,4
Affiliation: <sup>1</sup> College of Traditional Chinese Medicine and College of Life Sciences, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
<sup>2</sup> Evidence-Based Medicine Research Center, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
<sup>3</sup> School of Clinical Medicine, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
<sup>4</sup> Institute of Traditional Chinese Medicine and Health Development, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.
Conference/Journal: Front Cardiovasc Med
Date published: 2024 Feb 28
Other:
Volume ID: 11 , Pages: 1300319 , Special Notes: doi: 10.3389/fcvm.2024.1300319. , Word Count: 254
Background:
As a therapy to prevent and treat essential hypertension (EH), traditional Chinese exercises (TCEs) were widely used in clinical practice. However, there is a lack of strictly comparison of the antihypertensive efficacy of different TCEs, which not conducive to the selection of the best and most optimal treatment. This study aimed to perform a network meta-analysis to objectively evaluate which TCE has the best effects in assisting with lowering blood pressure.
Methods:
PubMed, Embase, the Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), VIP, SinoMed and Wanfang Data were searched for all randomized controlled trials (RCTs) on TCEs for the treatment of EH published up to July 10, 2023. RoB2.0 tool was utilized to evaluate the quality of the RCTs. The network meta-analysis was performed by R 4.1.2 and Stata 17.0. Weighted mean difference (WMD) was calculated for continuous outcomes.
Results:
A total of 29 studies, including 2,268 patients were included to analyze 6 different interventions. The network meta-analysis results presented that in comparison with control group, Tai Chi + antihypertensive medication [WMD = -10.18, 95% CI, (-14.94, -5.44)] is the most effective intervention for lowering systolic blood pressure (SBP), and Wuqinxi + antihypertensive medication [WMD = -10.36, 95% CI (-18.98, -1.66)] is the most effective intervention for lowering diastolic blood pressure (DBP).
Conclusion:
TCEs combined with antihypertensive medication may be able to achieve more prominent antihypertensive effects with Tai Chi and Wuqinxi potentially being the higher-priority options. However, well-designed randomized studies are warranted to further verify currently conclusion.
Keywords: Baduanjin; Tai Chi; essential hypertension; network meta-analysis; systematic review; traditional Chinese exercise.
PMID: 38481952 PMCID: PMC10935740 DOI: 10.3389/fcvm.2024.1300319