Author: Ping-An Zhu1, Qi-Qi Lu1, Zhi-Liang Li1, Rong-Liang Hu2, Shu Xu3, Lisa Brodersen4, Yuan-Xin Liu5, Howe Liu4, Xiao Bao1
Affiliation: <sup>1</sup> Department of Rehabilitation Medicine, Yuebei People's Hospital, Shaoguan, China.
<sup>2</sup> Department of Rehabilitation Medicine, Jiangmen Central Hospital, Guangdong, Jiangmen, China.
<sup>3</sup> Department of Rehabilitation Medicine, Shaoguan Railway Hospital, Shaoguan, China.
<sup>4</sup> Physical Therapy Program, Allen College, Waterloo, IA, United States.
<sup>5</sup> College of Sports and Health Science, Xi'an Physical Education University, Xi'an, China.
Conference/Journal: Front Aging Neurosci
Date published: 2023 Feb 1
Other:
Volume ID: 15 , Pages: 1096417 , Special Notes: doi: 10.3389/fnagi.2023.1096417. , Word Count: 258
Background:
At present, the effect of Tai Chi (TC) on lower limb function in patients with Parkinson's disease (PD) is controversial. Therefore, we conducted a meta-analysis on the influence of TC on lower limb function in PD patients.
Methods:
According to the PRISMA guidelines, seven databases were searched. Randomized controlled trials (RCTS) were selected and screened according to inclusion and exclusion criteria. We assessed the quality of the studies using the Cochrane Risk of Bias tool and then extracted the characteristics of the included studies. The random effect model was adopted, and heterogeneity was measured by I 2 statistic.
Results:
A total of 441 articles were screened, and 10 high-quality RCTs were with a total of 532 patients with PD met Our inclusion criteria. Meta-analysis showed that compared To control groups TC improved several outcomes. TC significantly improved motor function (SMD = -0.70; 95% CI = -0.95, -0.45; p < 0.001; I 2 = 35%), although The results were not statistically significant for The subgroup analysis of TC duration (SMD = -0.70; 95% CI = -0.95, -0.45; p = 0.88; I 2 = 0%;). TC significantly improved balance function (SMD = 0.89; 95% CI = 0.51, 1.27; p < 0.001; I 2 = 54%), functional walking capacity (SMD = -1.24; 95% CI = -2.40, -0.09; p = 0.04; I 2 = 95%), and gait velocity (SMD = 0.48; 95% CI = -0.02, 0.94; p = 0.04; I 2 = 78%), But Did Not improve endurance (SMD = 0.31; 95% CI = -0.12, 0.75; p = 0.16; I 2 = 0%), step length (SMD = 0.01; 95% CI = -0.34, 0.37; p = 0.94; I 2 = 29%), and cadence (SMD = 0.06; 95% CI = -0.25, 0.36; p = 0.70; I 2 = 0%).
Conclusion:
TC has beneficial effects on motor function, balance function, functional walking ability, and gait velocity, but does not improve walking endurance, stride length, and cadence.
Keywords: Parkinson’s disease; Tai Chi; balance; gait; motor function.
PMID: 36819715 PMCID: PMC9929552 DOI: 10.3389/fnagi.2023.1096417