Objective: This study investigated the placebo and nocebo effects of habitual and induced expectations. Methods: In Study 1, 95 participants (Mage = 19.65 ± 2.21 years, MBMI = 21.94 ± 2.55) were grouped according to habitual expectations (positive, neutral, or negative) and completed a 30-min moderate-intensity aerobic exercise, and their affective response, rating of perceived exertion (RPE), and heart rate variability (HRV) were measured before, during, and after the exercise. In Study 2, the participants from Study 1 were grouped according to induced expectations (control, positive, or negative) and completed a 30-min moderate-intensity aerobic exercise. Affective response, RPE, and HRV were measured before, during, and after exercise. Results: In Study 1, positive habitual expectations increased affective response during and after exercise [F(2, 92) = 2.959, p = .057, ηp2 = .060], and negative habitual expectations increased RPE during exercise [F(2, 92) = 5.174, p = .007, ηp2 = .101]. In Study 2, positive induced expectation increased affective response during [F(2, 86) = 5.492, p = .006, ηp2 = .113] and after exercise [F(2, 86) = 6.096, p = .003, ηp2 = .124] and was not affected by habitual expectation. Conclusion: The affective response during and after exercise is influenced by habitual and induced expectations. Positive expectations enhance affective benefits, while negative expectations reduce affective benefits.

Keywords: Habitual expectation; heart rate variability; induced expectation; nocebo effect.

PMID: 36121715 DOI: 10.1080/02701367.2022.2121372

Expectations Come True: The Placebo Effect of Exercise on Affective Responses