Effects of Vibration Training on Cognition and Quality of Life in Individuals With Multiple Sclerosis

Author: Feng Yang1, Pey-Shan Wen2, Francois Bethoux3, Yichuan Zhao4
Affiliation: <sup>1</sup> Department of Kinesiology and Health (FY), Georgia State University, Atlanta, GA, USA. <sup>2</sup> Department of Occupational Therapy (P-SW), Georgia State University, Atlanta, GA, USA. <sup>3</sup> Department of Physical Medicine and Rehabilitation, The Cleveland Clinic Foundation, Cleveland, OH, USA (FB). <sup>4</sup> Department of Mathematics and Statistics (YZ), Georgia State University, Atlanta, GA, USA.
Conference/Journal: Int J MS Care
Date published: May-Jun 2022
Other: Volume ID: 24 , Issue ID: 3 , Pages: 132-138 , Special Notes: doi: 10.7224/1537-2073.2020-095. , Word Count: 246

Multiple sclerosis (MS) detrimentally affects cognition and quality of life (QOL). Interventions that can improve cognitive deficit and QOL in individuals with MS are desired. This pilot study investigated the possible effects of vibration training on improving cognition and QOL in individuals with MS.

Eighteen adults with MS were randomized into 2 groups: training and control. The training group underwent 6 weeks of vibration training, and the control group maintained their normal lifestyle throughout the study. In both groups, before and after the training course, the disability status was evaluated by the Patient Determined Disease Steps scale and the Multiple Sclerosis Functional Composite (MSFC), cognitive function was assessed by the Behavior Rating Inventory of Executive Function-Adults (BRIEF-A) and the Buschke Selective Reminding Test (SRT), and QOL was gauged by the 36-item Short Form Health Survey (SF-36).

The training was well accepted by the participants, and no major adverse event was reported. All participants finished the entire protocol. Compared with the control group, the training group showed greater improvements in MSFC score, Metacognition Index score of the BRIEF, SRT score, and physical domain score of the SF-36.

These results suggest that vibration training could be an effective alternative training paradigm to enhance cognition and QOL in individuals with MS, and they provide an encouraging base to conduct a large-scale clinical trial.

Keywords: Psychosocial issues in MS; Quality of life in MS; Rehabilitation strategies and therapy and MS; Vibration training.

PMID: 35645623 PMCID: PMC9135366 DOI: 10.7224/1537-2073.2020-095